Sepsis can occasionally very rapidly develop into septic shock, which can sometimes be fatal. If the inflammatory response is sufficiently strong, the major organ systems are affected and begin to fail. Each hour of delay before adequate antibiotic treatment leads to an increased risk of the patient dying during care. Therefore early detection is essential. Most likely, the patient's own experience can help to identify these patients at an early and treatable stage. At present there are no studies on the patient's experience of care.

The MISSIS study looks at the hypothesis that improved assessment and communication lead to earlier identification, thus improving the prognosis in cases of sepsis.

A more accurate care assessment of sepsis patients by the ambulance service can reduce the delay to treatment and thereby increase survival and reduce the risk of complications.